Sucralose is a chemical sweetener made by adding chlorine atoms to regular table sugar. The artificial sweetener isn’t recognised, or processed, by the body, so it has a zero-calorie content.
Sucralose was discovered by accident just 40-years ago, and its low cost, combined with shelf stability, has made it very popular with food and beverage producers. The sucralose market is now worth over $3.75 billion per year, but there are growing concerns about its impact on our health.
Several studies have shown that sucralose consumption has effects on glucose and insulin metabolism while disrupting the balance of the gut microbiome. Previously, animal studies demonstrated changes in the gut bacteria composition with sucralose intake, but until recently its impact on humans had remained unclear.
In this article we explore a 10-week clinical trial conducted in healthy young adults to investigate the effects of long-term low-dose sucralose ingestion on gut microbiota and its impact on glucose and insulin levels.