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Ribose & the Pentose Phosphate Pathway in Nerve Repair

Ribose & the Pentose Phosphate Pathway in Nerve Repair

A new breakthrough study in Cell reveals a surprising and powerful role for one of the body’s fundamental sugar-processing systems: the pentose phosphate pathway. The researchers found that in spinal cord injuries, oral intake of ribose led to the building of new...

Ribose & the Pentose Phosphate Pathway in Nerve Repair

New research shows the pentose phosphate pathway and ribose play a key role in nerve repair. Oral ribose supported nerve cell regeneration in spinal cord injuries, highlighting how sugar-derived molecules aid cellular repair.

Trehalose: A Smart Sugar for Fruit Quality and Metabolic Stability

Trehalose: A Smart Sugar for Fruit Quality and Metabolic Stability

Trehalose does more than provide sweetness, it plays a role in cellular stability. In a recent study on postharvest Kyoho grapes, trehalose treatment enhanced antioxidant activity, reduced microbial decay and helped preserve fruit quality by influencing phenolic and amino acid metabolism. These findings reinforce an important principle: not all sugars behave the same. Certain sugars, such as trehalose, interact with biological systems in ways that support resilience and metabolic balance beyond simple energy provision.

Dr. Johannes Coy on the Future of Sweetness and Health

Dr. Johannes Coy on the Future of Sweetness and Health

In Top Magazin Frankfurt, Dr. Johannes Coy shares how his TKTL1 research reshaped his understanding of sugar, leading to functional alternatives like tagatose, galactose, and mannose. His vision: sweets that taste indulgent while supporting real metabolic health.

Galactose in Parenteral Nutrition: A Metabolic Rationale Worth Investigating

Galactose in Parenteral Nutrition: A Metabolic Rationale Worth Investigating

A recent hypothesis paper suggests that adding galactose to parenteral (IV) nutrition—currently based almost entirely on glucose—may offer metabolic benefits for premature infants. The authors highlight that existing IV formulations don’t mirror the natural balance of glucose and galactose found in human milk, and propose that a more milk-like carbohydrate profile could better support early development.

Allulose Shows Low Cariogenic Potential in New Oral Microbiome Study

Allulose Shows Low Cariogenic Potential in New Oral Microbiome Study

A recent study published in Frontiers in Cellular and Infection Microbiology examined how different sugars influence the development of dental biofilms and microbial balance in the mouth. The research focused particularly on Allulose, a rare sugar, and assessed its potential to promote or prevent conditions associated with tooth decay.

How Common Sugars in Drinks Accelerate Colorectal Cancer

How Common Sugars in Drinks Accelerate Colorectal Cancer

A recent study published in Nature Metabolism (September 2025) has provided compelling new evidence that the type and combination of sugars commonly found in sugar-sweetened beverages (SSBs) can accelerate the progression and spread of colorectal cancer (CRC).

PDGFB and Lung Cancer: When Sugar Metabolism Fuels Tumor Growth

PDGFB and Lung Cancer: When Sugar Metabolism Fuels Tumor Growth

A new study shows how PDGFB accelerates lung cancer by driving the Warburg effect, where cells switch from healthy combustion to fermentation of glucose — a process fueled by the TKTL1 gene, discovered by Dr. Johannes Coy. The Dr. Coy Principle, built on five nutritional pillars including funtional sugars (galactose, mannose, tagatose) that cancer cells cannot exploit, offers a science-based way to counteract this metabolic shift.

GLP-1 Breakthroughs and Dr. Coy’s Sugars Are Two Sides of the Same Coin

GLP-1 Breakthroughs and Dr. Coy’s Sugars Are Two Sides of the Same Coin

As new research shows GLP-1 drugs may slow Alzheimer’s progression by improving sugar metabolism and reducing inflammation, it’s clear that brain health starts with metabolic health. But while GLP-1 receptor agonists treat existing imbalances, Dr. Coy’s sugars—like galactose, isomaltulose, and tagatose—prevent them by supporting stable blood sugar and lowering dietary inflammation.

New Insights into Metabolic Health and Lung Cancer: Rethinking Our Sugar Choices

New Insights into Metabolic Health and Lung Cancer: Rethinking Our Sugar Choices

A major new study has uncovered distinct metabolic markers linked to lung cancer in non-smokers, challenging the long-held belief that external carcinogens are the primary cause of the disease. Research published in Nature suggests that altered sugar metabolism and mitochondrial dysfunction are key contributors to cancer growth.

Tagatose: A Tooth-Friendly Sugar?

Tagatose: A Tooth-Friendly Sugar?

Tooth decay affects 2.3 billion people worldwide, with sugar being a major cause. While cutting sugar completely isn’t realistic—or healthy—studies show tagatose is a sweet, tooth-friendly alternative that supports dental health.

Ribose: Help Your Muscles Increase Power Output

Ribose: Help Your Muscles Increase Power Output

Ribose, a naturally occurring sugar in the body and a key building block of ATP, helps boost muscle cell energy. Supplementing with ribose can enhance power output and improve exercise capacity, supporting better performance and recovery.