Learn more about Dr. Coy and the creation of his sugar solutions.

Dr Johannes Coy is a world-renowned scientist whose research focuses on the health benefits of sugar awareness. Dr Coy has made a number of important genetic discoveries which change our understanding of cancer and nutrition and make him the leading expert on sugars.

Book: Fit with Sugar, by Dr Johannes Coy

Dr Coy has written several books about cancer nutrition. His latest book, Fit with Sugar, is now available. In this book, you’ll discover the evolutionary role of sugar in the human body. Consuming too much conventional sugar isn’t good for our health, but with the right sugars, we can stop cell ageing, keep the brain fit, protect against diseases and switch on fat burning. Find out how you can maintain physical and mental performance using natural low- glycaemic sugars and sugar substitutes. The book includes many delicious recipes for cakes, snacks and desserts, so you can implement a sugar-conscious diet easily and intelligently, without giving up sweet treats.

Buy the book: Cancer-Fighting Diet: Diet and Nutrition Strategies to Help Weaken Cancer Cells and Improve Treatment, by Dr Johannes Coy.

Research & Resources

A glycolytic shunt via the pentose phosphate pathway is a metabolic checkpoint for nervous system sensory homeostasis and axonal regeneration

This study looked at how a specific energy pathway in cells, called the pentose phosphate pathway (PPP), supports nerve function and repair. The researchers found that in peripheral nerves, this pathway helps nerves sense touch and recover after injury by supplying the building blocks and antioxidant support needed for repair. In contrast, this pathway is largely inactive in the spinal cord, which helps explain why spinal cord injuries heal so poorly. When the scientists reactivated this pathway, either by boosting a key enzyme or by giving ribose, they saw improved nerve regrowth and functional recovery. Overall, the study shows that restoring this metabolic pathway can play an important role in nerve regeneration and recovery after injury.

Dermal benefits of topical D-ribose

This study explored the effects of a topical D-ribose-based formulation on skin aging and glycation-related damage. Participants applied the product daily over several weeks, and the majority reported improvements in skin smoothness, radiance, and reduced dullness. The study highlighted that D-ribose may help reduce Maillard reaction-related glycation in the skin, supporting collagen health and overall skin elasticity, suggesting its potential as an ingredient for maintaining a healthier, more youthful skin appearance.

Effect of D-ribose supplementation on delayed onset muscle soreness induced by plyometric exercise in college students

This study examined whether D-ribose supplementation could support recovery after intense plyometric exercise in untrained men. Participants performed exercise designed to induce delayed onset muscle soreness and were given either D-ribose or a placebo before and after training. The results showed that those taking D-ribose reported reduced muscle soreness and had lower blood markers of muscle damage compared with placebo, indicating a potential role for D-ribose in easing post-exercise muscle damage and supporting recovery.

The influence of D-ribose ingestion and fitness level on performance and recovery.

Skeletal muscle adenosine triphosphate (ATP) levels are severely depleted during and following prolonged high intensity exercise. this study was designed to determine what influence D-ribose might have on muscular performance, recovery, and metabolism during and following a multi-day exercise regimen.

A Combination of Nicotinamide and D-Ribose (RiaGev) Is Safe and Effective to Increase NAD+ Metabolome in Healthy Middle-Aged Adults: A Randomized, Triple-Blind, Placebo-Controlled, Cross-Over Pilot Clinical Trial

This study evaluated the effects of RiaGev, a combination of nicotinamide and D-ribose, on NAD+ metabolome enhancement in healthy middle-aged adults. Supplementing 1520 mg twice daily for 7 days significantly increased NAD+ metabolites, reduced blood glucose without altering insulin secretion, and decreased waking cortisol levels. Participants also reported less fatigue and improved mental focus, with no adverse effects observed, demonstrating RiaGev’s safety and efficacy.

Prevalence of auto-antibodies against D-ribose-glycated-hemoglobin in diabetes mellitus

High blood sugar levels lead to the formation of advanced glycation end products (AGEs), which contribute to the progression of diabetes. In a study, structural changes in hemoglobin (Hb) caused by D-ribose were observed, potentially triggering an autoimmune response in diabetic patients. Autoantibodies against D-ribose glycated-Hb were found to be prevalent in diabetic patients’ blood, indicating their potential as biomarkers for diabetes progression.

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