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Expanding the Nutritional Perspective: Beyond the Ketogenic Diet in Modulating the Tumour Microenvironment

The recent publication of The Clinical Research Framework Proposal for Ketogenic Metabolic Therapy in Glioblastoma marks a key step forward in using metabolic interventions for cancer treatment. Although the ketogenic diet shows promise in targeting the metabolic weaknesses of glioblastoma, exploring wider nutritional strategies could offer more ways to influence the tumour microenvironment.

Unlocking TKTL1 – Part 2

Unlocking TKTL1 – Part 2

TKTL1 is a special gene that emerged during the evolution of mammals. Numerous genetic changes optimized this gene, and the enzyme it created, over the course of 300 million years.

Unlocking TKTL1 – Part 1

Unlocking TKTL1 – Part 1

TKTL1 is a special gene that emerged during the evolution of mammals. Numerous genetic changes optimized this gene, and the enzyme it created, over the course of 300 million years.

Train your Muscles with Sugar: Galactose’s Metabolic Capabilities

Train your Muscles with Sugar: Galactose’s Metabolic Capabilities

Imagine eating a chocolate bar to help train your muscles to burn energy more efficiently.

A recent study proves galactose’s ability to make our muscles more efficient. Researchers investigated how changing the type of sugar (from glucose to galactose) drastically affects the energy metabolism of our muscle cells.

Are Fizzy Drinks Impacting a Rise in Adolescent Obesity?

Are Fizzy Drinks Impacting a Rise in Adolescent Obesity?

In the realm of food additives, few have stirred as much controversy and debate as aspartame. With its widespread use as a sugar substitute in over 6,000 products, from diet sodas to chewing gum, aspartame has long been a subject of scrutiny and concern.

Aspartame: how bad can it be?

Aspartame: how bad can it be?

In the realm of food additives, few have stirred as much controversy and debate as aspartame. With its widespread use as a sugar substitute in over 6,000 products, from diet sodas to chewing gum, aspartame has long been a subject of scrutiny and concern.

Empowering Women with Cancer: An Interview with Caroline Justich, Founder of Be accepted

Empowering Women with Cancer: An Interview with Caroline Justich, Founder of Be accepted

Inspirational and cancer-defying, Caroline Justich is the founder of Be accepted, Home of the smart 8, an initiative for women diagnosed with cancer. Founded in cooperation with the European Society of Radiology, the program offers a magazine and online platform focused on building a bridge between western medicine and complementary evidence-based methods to support therapy, life quality and recovery.

Glucose, Growth and Stress

Glucose, Growth and Stress

For the first time Ramon Spectroscopy is allowing scientists to see inside cells and quantify exactly where energy is being used. This revolutionary technique is revealing exactly how glucose is fueling cancer growth in multiple ways.

Cancer Initiation

Cancer Initiation

A remarkable new study published in the British Journal of Cancer has shown that excess glucose in the blood (known as hyperglycemia) reprograms cellular energy pathways, and changes their genetic regulation. Scientists were able to clearly demonstrate how cancerous cells are enabled by elevated glucose levels, allowing them to spread round the body and grow into more dangerous types of tumor.

Metabolic Reprogramming

Metabolic Reprogramming

A remarkable new study published in the British Journal of Cancer has shown that excess glucose in the blood (known as hyperglycemia) reprograms cellular energy pathways, and changes their genetic regulation. Scientists were able to clearly demonstrate how cancerous cells are enabled by elevated glucose levels, allowing them to spread round the body and grow into more dangerous types of tumor.

The Warburg Effect: Diet and Cancer (the latest evidence)

The Warburg Effect: Diet and Cancer (the latest evidence)

In 1931 Otto Warburg won a Nobel Prize for his research into tumours, and cancer cells. He discovered that healthy cells and cancer cells ‘breathe and eat’ (metabolise) very differently. Ever since his ground-breaking discovery over 90 years ago, scientists have been researching these critical metabolic differences. Thousands of scientific papers have been published to understand why, and how, cancer cells rewire their metabolism.