This study investigated metabolomic markers associated with the development of central adiposity in young adults. Participants with incident central adiposity gain had higher levels of blood erythritol compared to those with stable adiposity. Participants with higher baseline hemoglobin A1c (HbA1c) levels also had significantly higher blood erythritol. Erythritol was found to be synthesized from glucose through the pentose-phosphate pathway, suggesting its potential role in the association between erythritol and obesity in young adults.
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